PhosphoSens Kinase Sensor Peptide CSKS-AQT0101

Note: Type K denotes Assay Kits, B denotes Bulk Sensor Peptide, RA denotes Reagent

Number of assays: 96-192 assays or wells per kit, and about 1000-2000 assays per 1mg of bulk sensor peptide (depending on if 50µL or 25µL is used for the final reaction volume per well, respectively)

Kit accessories:

• Included: Sealing film, qualified plates (white, low protein binding): 96- or 384-well format, paddle to seal film, and all necessary reagents.
  • All kits include the following components: PhosphoSens Substrate, 1 mM, ATP Solution, 100 mM, DTT Solution, 1 000 mM, Enzyme Reaction Buffer, 10X, Enzyme DilutionBuffer, 5X, EGTA Solution, 550 mM
• Not included: Enzyme (Kinase enzyme must be obtained from a commercial supplier, see recommendation in the product list here)

Products Description:

• CSKS-AQT0101B: Bulk Sensor Peptide Substrate recommended for ALK [C1156Y], ALK [F1174L], ALK [G1269A], ALK [L1196M], ALK [R1275Q], ALK [T1151‐L1152 INS T], ALK:NPM1 (NPM1‐ALK), BTK, BTK [C481S], FGFR3 [G697C], FGFR3 [K650E], FGFR3 [K650M], FGFR3 [V555L], ITK, ROS1 [G2032R] PhosphoSens-Kinetic Kinase Acitivity Assays
• CSKS-AQT0101K: Assay Kit recommended for ALK [C1156Y], ALK [F1174L], ALK [G1269A], ALK [L1196M], ALK [R1275Q], ALK [T1151‐L1152 INS T], ALK:NPM1 (NPM1‐ALK), BTK, BTK [C481S], FGFR3 [G697C], FGFR3 [K650E], FGFR3 [K650M], FGFR3 [V555L], ITK, ROS1 [G2032R] PhosphoSens-Kinetic Kinase Acitivity Assays

Shipping: Dry ice for kits, room temperature for bulk sensor peptide

Storage: -20°C

Shelf Life: 9 months

HGNC Targets (Common) Name: ALK [C1156Y], ALK [F1174L], ALK [G1269A], ALK [L1196M], ALK [R1275Q], ALK [T1151‐L1152 INS T], ALK:NPM1 (NPM1‐ALK), BTK, BTK [C481S], FGFR3 [G697C], FGFR3 [K650E], FGFR3 [K650M], FGFR3 [V555L], ITK, ROS1 [G2032R]

Consolidated target aliases:

• receptor tyrosine kinase
• ros proto-oncogene 1
• ALK; ALK receptor tyrosine kinase; Anaplastic lymphoma kinase; Anaplastic lymphoma kinase (Ki-1); Anaplastic lymphoma receptor tyrosine kinase; CD246; ALK tyrosine kinase receptor
• il2-inducible t cell kinase 
• FGFR3; Fibroblast growth factor receptor 3; CD333; CEK2; FGFR-3; HSFGFR3EX; JTK4; FGF-R3 wt; Heparin-binding growth factor receptor; SAM3; ACH; achondroplasia, thanatophoric dwarfism
• BTK; Bruton tyrosine kinase; IMD1; AGMX1; AT; BPK; PSCTK1; ATK; Bruton's tyrosine kinase; XLA; Agammaglobulinaemia tyrosine kinase; B cell progenitor kinase; BPK